Influence of Age on Ginkgo Biloba Phytochemicals in Antimicrobial Activity Perspective

  • Priyanka Sati Biotechnological Applications, G.B. Pant National Institute of Himalayan Environment and Sustaniable Development, Kosi-Katarmal, Almora 263 643, Uttarakhand, India; Department of Biotechnology, Graphic Era University, Dehradun-248002, Uttarakhand, India
  • Anita Pandey Biotechnological Applications, G.B. Pant National Institute of Himalayan Environment and Sustaniable Development, Kosi-Katarmal, Almora 263 643, Uttarakhand, India
Keywords: Ginkgo biloba, antimicrobial activity, antioxidants, phenolics, flavonoid glycosides


Ginkgo biloba is widely used for its pharmaceutical potential due to it’s medicinal value. Its medicinal properties are directly related to the presence of the phytochemical constituents, mainly the terpenes trilactone (ginkgolides and bilobalide) and flavonoid glycosides that are likely to be influenced by a number of soil, biogeographic and climatic factors as well as the age of the tree. The present study is aimed to investigate the influence of the age of Ginkgo tree with respect to the total phenolic and total flavonoid content, antioxidants and flavonoid glycosides along with the antimicrobial activity following Ultraviolet Spectroscopy and High Performance Liquid Chromatography.The results exhibited great variability in all the phytochemicals, under study, showing significant decline with ageing of the Ginkgo tree. However, the antimicrobial activity that was determined in terms of strong inhibition on a range of microorganisms (bacteria, actinomycetes and fungi) in plate assays, varied in this respect to limited extent.


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