Influence of Age on Ginkgo Biloba Phytochemicals in Antimicrobial Activity Perspective
Keywords:
Ginkgo biloba, antimicrobial activity, antioxidants, phenolics, flavonoid glycosidesAbstract
Ginkgo biloba is widely used for its pharmaceutical potential due to it’s medicinal value. Its medicinal properties
are directly related to the presence of the phytochemical constituents, mainly the terpenes trilactone (ginkgolides
and bilobalide) and flavonoid glycosides that are likely to be influenced by a number of soil, biogeographic and
climatic factors as well as the age of the tree. The present study is aimed to investigate the influence of the age of
Ginkgo tree with respect to the total phenolic and total flavonoid content, antioxidants and flavonoid glycosides
along with the antimicrobial activity following Ultraviolet Spectroscopy and High Performance Liquid
Chromatography. The results exhibited great variability in all the phytochemicals, under study, showing
significant decline with ageing of the Ginkgo tree. However, the antimicrobial activity that was determined in
terms of strong inhibition on a range of microorganisms (bacteria, actinomycetes and fungi) in plate assays, varied
in this respect to limited extent
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